NATURAL METABOLISM SUPPORT†
Natural GLP-1 Supplement
4.82,000+ customersStimulant-free appetite suppressant capsules that support your body’s own GLP-1.†
OEA, BIOMEnd® butyrate and konjac fiber, fully dosed. Take 3 capsules 30 minutes before a meal.
125 mg OEAFullness & GLP-1 signaling†
500 mg BIOMEnd®Gut-brain axis & GLP-1 support†
Zero stimulantsNo caffeine, no jitters
5 powerful activesNo hidden doses
Ships by Tomorrow
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- 84 capsules · 28 servings per bottle
- Subscriptions: skip, edit or cancel anytime
The 14-Day Ozzi Challenge
Take it for 14 straight days. If your cravings and food noise aren’t quieter, we’ll refund your first bottle.
GLP-1 may cause slight nausea from fullness. If nausea occurs, break a single serving apart into 3 doses over several hours. Discontinue use immediately if your appetite is gone for 12+ hours after use.
Why this blend?
A lot of appetite suppressant pills lean on caffeine to blunt hunger. This one works with the signals your gut already sends. OEA tells your brain you’ve eaten, OEA and butyrate both support natural GLP-1 production, and konjac fiber takes up space. No jitters, no crash.†
The 14-Day Ozzi Challenge
Take it for 14 straight days. If your cravings and food noise aren’t quieter, we’ll refund your first bottle.
Directions and Supplement Facts
Take 3 capsules with at least 12 oz of water 30 minutes before a meal, up to twice a day. Leave at least 4 hours between servings.
See the full formula and directionsNATURAL GLP-1 SUPPLEMENT
Your body already makes GLP-1.
This formula supports it.†
GLP-1 isn’t only a medication. It’s a hormone your own gut releases every time you eat.
A natural GLP-1 supplement doesn’t contain a drug or copy one. It supports the GLP-1 your body already makes, the signal that tells your brain a meal is doing its job.†
The fullness hormone your gut releases after every meal.
When food reaches your small intestine, L-cells in your gut lining release GLP-1. It tells your brain you’ve eaten, slows how fast your stomach empties so fullness lasts, and helps your body release insulin after a meal. Your own GLP-1 is short-lived: an enzyme called DPP-4 starts breaking it down within minutes, often before it leaves the gut. Source
GLP-1 is one of the clearest fullness signals scientists have measured.
Researchers have tested what GLP-1 itself does to appetite in people.
- 12% less at the next meal. In a randomized, placebo-controlled trial, 20 healthy men given a GLP-1 infusion felt fuller after breakfast and ate 12% less at a free-choice lunch. Source
- The same result across studies. A meta-analysis pooling 115 people found GLP-1 infusion cut how much they ate by 11.7%, in both lean and overweight adults, and slowed stomach emptying. Source
- The signal can run low. In a small study of lean women and women with obesity, the GLP-1 response to a carbohydrate meal was much weaker in the women with obesity. Source
These studies gave GLP-1 itself by IV. They show what the hormone does, not results from this supplement.
03 / HOW THIS FORMULA SUPPORTS IT
How this natural GLP-1 supplement supports the signal.†
Adds your gut’s own fullness molecule.†
OEA is the fullness signal your gut makes from the fat in a meal. In lab research it activates PPAR-alpha and GPR119, the receptor on the L-cells that release GLP-1. You get 125 mg, 30 minutes before you eat.†
Supports the cells that send the signal.†
Butyrate fuels your gut lining, and in mouse and cell studies it stimulated the L-cells that release GLP-1 and PYY. BIOMEnd® reached peak blood levels in just 20 minutes in a human study.†
Gives your stomach something to register.†
Glucomannan soaks up water and swells into a gel. That volume gently stretches your stomach, and stretch is one of the signals your vagus nerve reports to your brain as fullness.†
WHAT’S INSIDE. WHY IT’S HERE.
5 powerful actives.
No hidden doses.
Tap an ingredient to see what it does and what the research actually tested. Amounts are per 3-capsule serving.
INSIDE THE FORMULA01 / 05
OEAFullness signalingConcept illustration. Ingredient proportions are not shown.
OEA
Fullness signaling
125 mgper servingOEA: your body’s fullness signal.†
OEA (oleoylethanolamide) is a molecule your small intestine makes after a meal with fat in it. It’s one of the ways your gut tells your brain you’ve eaten. Each serving gives you 125 mg to support appetite control and natural GLP-1 production.†
Oleoylethanolamide. 125 mg per 3-capsule serving.
What does the research say?
In rats, OEA reduced food intake through PPAR-alpha, a fullness sensor (Fu, Nature 2003). In mouse and cell studies, it triggered GLP-1 release from the gut’s L-cells through GPR119 (Lauffer, Diabetes 2009). In people, a 60-day randomized trial found OEA improved hunger and fullness.
See what each OEA study testedKonjac
Water-binding fiber
500 mgper servingFiber that takes up space.
Glucomannan is a soluble fiber from konjac root. It soaks up water and forms a thick gel, which is exactly why you take it with a full glass of water.†
Glucomannan extract from konjac root. 500 mg per serving.
What does the research say?
Glucomannan is one of the most studied fibers for fullness. It swells into a gel in your stomach, which is why every serving goes down with a full glass of water.
See the fiber evidenceBIOMEnd®
GLP-1 support
500 mgper servingButyrate, in the form with human absorption data.
Butyrate is the short-chain fatty acid your gut bacteria make from fiber, and the main fuel for the cells lining your colon. In mouse and cell studies, it stimulated the L-cells that release GLP-1. BIOMEnd® pairs it with the amino acid L-lysine instead of sodium.†
500 mg L-lysine butyrate as BIOMEnd® per serving. That’s the whole ingredient, lysine included, not pure butyric acid.
What does the research say?
In a 2025 human crossover study, BIOMEnd reached peak blood butyrate in 20 minutes, about 5× the peak of tributyrin.
See the butyrate researchAfrican mango
Botanical support
150 mgper servingAfrican mango seed extract.
Irvingia gabonensis seed has been studied for weight and metabolic markers in small trials. We include 150 mg per serving as a supporting botanical.
Irvingia gabonensis seed extract. 150 mg per serving.
What does the research say?
In a 10-week randomized trial, a standardized African mango seed extract supported healthy body weight, waist size and metabolic markers compared with placebo.
See the extract studyMetabolex®
Blood sugar support
10 mgper servingChromium, as Metabolex®.
Chromium is an essential mineral that helps insulin move sugar into your cells. Metabolex® supplies 300 mcg per serving, bound to ursolic acid, to support blood sugar control.†
10 mg chromium polyursolate supplies 300 mcg chromium (857% DV). These are two ways of describing the same ingredient, not separate doses.
What does the research say?
Chromium has decades of research behind its role in insulin signaling and glucose metabolism, and it’s one of the most studied minerals for blood sugar support.†
Read about chromiumEVERY INGREDIENT. EVERY AMOUNT.
Know exactly
what you’re taking.
Every amount is printed, so you can check our doses against the studies yourself.
84 capsules3 capsules per serving
28 servings per bottle
28 servings per bottle
View Supplement Facts
Supplement Facts
Serving size: 3 capsulesServings per container: 28
| Amount per serving | Amount | % Daily Value |
|---|---|---|
| Chromium (as chromium polyursolate) (Metabolex®) | 300 mcg | 857% |
| L-Lysine Butyrate (as BIOMEnd®) | 515 mg | ** |
| Glucomannan Extract (Amorphophallus konjac) (root) | 500 mg | ** |
| Inulin (from Chicory Root) | 190 mg | ** |
| African Mango Extract (Irvingia gabonensis) (seed) | 150 mg | ** |
| Oleoylethanolamide (OEA) | 125 mg | ** |
| Chromium polyursolate (as Metabolex®) | 10 mg | ** |
*Daily Values based on a 2,000 calorie diet.
**Percent Daily Values (DV) not established.
Other ingredients: Vegetable Capsule (Hypromellose), Nu-FLOW® Rice (Oryza sativa) Hull Powder, Organic Nu-MAG® Organic Rice Extract Blend.
Suggested use: Take three (3) capsules once or twice daily with at least 12 oz of water. For best results, take 30 minutes before a meal to help reduce portion sizes, or 30 minutes after a meal to extend satiety and reduce snacking. Do not exceed one dose within 4 hours.
Caution: Not intended for use by persons under 18. Do not use if pregnant, nursing, or planning to become pregnant. Consult your healthcare provider before use, especially if you are taking medication or have a medical condition. Discontinue use and consult a healthcare professional if any adverse reaction occurs. Always take with water. Store in a cool, dry place. Keep out of reach of children.
Allergen statement: This product is manufactured in a facility that also processes other products which may contain milk, eggs, fish, shellfish, tree nuts, peanuts, soy, wheat, and sesame.
Customer reviews
From Crave Crusher customers.
These reviews are for the original Crave Crusher Capsules. The new formula adds OEA; these customers did not review the updated blend.
What people are saying
4.8
Based on 21 reviews
90% would buy again 20 answers
Curbs hunger 4.2
Not at allCompletely
Customer photos
Most buyers say the capsules help with hunger between meals and the urge to snack.
Some buyers mention it takes a couple of weeks of daily use before they notice a change.
Many buyers also like that the capsules are easy to take at home or at work with no drink to mix.
Summary by Ozzi, based on 22 reviews
Showing 20 of 21 reviews
I keep it next to my sink so I remember to take it every morning. I had definitely helped reduce my hunger in the mornings!
Verified buyer
I have to admit I complained about the smell and they were so quick to respond!! Refunded one of my bags. I continued with the process and tried a shaker bottle and straw. The taste is great. Smell takes some getting used to. But it is a process. This is a fantastic company.!! The capsules are great.
Verified buyer
Really does help curb cravings and appetite control. I haven't had any issues with any side effects either.
Verified buyer
LOVE the capsules! I tried the sticks almost a year ago. I could feel the effects, but my partner hated the smell which made it hard to be consistent about it. The capsules are a game changer. I can take them at home and at work which has made staying consistent way easier.
I struggle with overeating and the capsules really help reduce that consistent food noise and help me stop when I’m full.Verified buyer
I like the ease of the capsules. All of the flavors I’ve tried are great, especially the cherry limeade. Definitely recommend both products!
Verified buyer
What else can I say besides WOW?! This has been an amazing support in my weight loss journey. I feel like I actually have control over my cravings for a change.
Verified buyer
I noticed some effects right away. I just hit my 2 week mare & noticed a drastic change in a lower appetite, not sure if it's a fluke but I hope not.
Verified buyer
I have IBS-D so I was worried this could make my problem worse but actually it seems to help. I definitely feel full but not painful. I’m hoping the butyrate will help reduce inflammation, but it’s too early to say. Food noise is still present but more manageable.
Verified buyer
good product! The new cherry lime is so good!
Verified buyer
It helps me get from meal to meal! I love it!
Verified buyer
I take it in the evening when my hunger strikes to keep from eating.
It works.Verified buyer
The capsules really help if you stick with them!
Verified buyer
Yes, I found that it really did reduced my hunger. I was not thinking about food nearly as much. And, I could get thru the afternoon pretty easily, compared to pre-Ozzi use! I am now a subscriber and don't want to go without it!!
Verified buyer
I like having the option of the capsules for those times when I’ve had plenty of water and don’t need to prepare and drink another 16 ounces at that time.
Verified buyer
CANCEL ANY AND ALL FUTURE SUBSCRIPPTIONS. DO NOT SEND ANY MORE. I HAVE MOR THAN I CAN FINISH. STOP SENDING
Verified buyer
Ozzi replied
Hi, you can cancel your subscription at https://heyozzi.com/a/account/login.
We send reminders 3 days post-purchase and 3 days prior to renewal to make it super easy to manage your account at any time.It really made a difference in turning off the intrusive thoughts about food. Im gonna keep using it! Thanks!
Verified buyer
Really curbside the urge to snack at night! Loving it so far!!
Verified buyer
Some days OZZI seems to work better than others but its probable because of the craziness in my life. Love the stuff. It definitely helps to get rid of the food noise.
Verified buyer
I love that it crushed craving, is easy to take and fits into my lifestyle
Verified buyer
Not sure how the elements are helping. It is too soon since I started.
Verified buyer
THE SCIENCE, IN PLAIN ENGLISH
The science behind
every ingredient.
Every active in this natural GLP-1 supplement has published research behind it. Here’s what scientists found, in plain English, with links so you can read it yourself.
HERO INGREDIENTS
OEA + BIOMEnd® butyrate: two fullness signals
OEA is the fullness molecule your gut makes from the fat in a meal. Butyrate is the fuel your gut lining runs on, made from fiber. Both connect to the L-cells that release GLP-1, from two different directions. Together they’re the core of the formula.
Tap a study to see what it found.
How OEA supports GLP-1
In mouse and cell studies, OEA activated GPR119, a receptor on the gut’s L-cells, and triggered GLP-1 release. It also reduced food intake in rats by switching on PPAR-alpha, a fullness sensor. Two pathways, one molecule your gut already makes.
Read Lauffer et al., 2009 Read Overton et al., 2006 Read Fu et al., 2003OEA and appetite in people
In a 60-day randomized trial of adults with obesity, OEA taken at 125 mg twice a day improved hunger, desire to eat and feelings of fullness compared with placebo. That’s the same daily amount as two servings.
Read Payahoo et al., 2018Butyrate: gut fuel and GLP-1 signaling
Butyrate is the main fuel for the cells lining your colon and helps maintain your gut barrier. In mouse and cell studies, it stimulated the L-cells that release GLP-1 and PYY.
Read the colon-cell study Read the L-cell studyBIOMEnd®: in your blood in 20 minutes
In a 2025 human crossover study, BIOMEnd® L-lysine butyrate reached peak blood butyrate at 20 minutes, about 5× the peak of tributyrin. It pairs butyrate with the amino acid L-lysine instead of sodium.
Read the BIOMEnd study Explore the dedicated butyrate formulaKonjac: fiber that expands
Glucomannan absorbs water and forms a thick gel in your stomach. A meta-analysis of randomized trials found it supported healthy body weight in adults, which is why it’s one of the best-known fibers for fullness.
Read the glucomannan meta-analysisAfrican mango: weight and metabolic research
In a 10-week randomized, placebo-controlled trial, a standardized African mango seed extract supported healthy body weight, waist size, cholesterol and blood sugar markers.
Read Ngondi et al., 2009Chromium: blood sugar support
Chromium is an essential mineral that helps insulin move glucose into your cells. It’s one of the most researched minerals for blood sugar support, and each serving provides 300 mcg as Metabolex®.
Read the NIH chromium overviewWhat’s in this natural GLP-1 supplement?
A stimulant-free natural GLP-1 supplement in capsule form. Each 3-capsule serving has 125 mg OEA, 500 mg BIOMEnd® butyrate, 500 mg konjac glucomannan, 150 mg African mango and 300 mcg chromium to support appetite control, natural GLP-1 production and blood sugar control.†
What is a natural GLP-1 supplement?
It’s a supplement that supports the GLP-1 your body already makes, rather than supplying a drug. GLP-1 is a hormone your gut releases after meals that helps tell your brain you’re full. These capsules use OEA and BIOMEnd® butyrate, two ingredients researched for their role in natural GLP-1 production.†
What does GLP-1 do in the body?
GLP-1 is a hormone your small intestine releases after you eat. It signals fullness to your brain, slows how fast your stomach empties and helps your body release insulin after meals. Your body breaks it down within minutes, so the signal is short-lived.
Is a natural GLP-1 supplement the same as a GLP-1 medication?
No. GLP-1 medications are prescription drugs built to act like the hormone for far longer than your own GLP-1 lasts. A natural GLP-1 supplement contains no drug. This one uses OEA and BIOMEnd® butyrate, ingredients researched for their role in supporting the GLP-1 your gut already makes.†
Are these appetite suppressant pills?
They’re appetite support capsules, without the stimulants many appetite suppressant pills rely on. There’s no caffeine. The formula uses OEA, butyrate and konjac fiber to support fullness and appetite control.†
Can I take it after stopping a GLP-1 medication?
Talk to your prescriber first. Ozzi isn’t a replacement for a prescribed medication. Plenty of Ozzi customers do come to us for appetite support after they’ve stopped one, and every ingredient amount is on the label so your prescriber can review it.
What is OEA, and why is it in Ozzi?
OEA (oleoylethanolamide) is a fullness molecule your small intestine makes from dietary fat. It signals your brain along the gut-brain axis and, in lab research, supports GLP-1 release through a receptor called GPR119. It isn’t a cannabinoid and it isn’t a stimulant. Each serving has 125 mg.† See the OEA studies and what they tested.
How much OEA is in each serving?
125 mg per 3-capsule serving. A 60-day appetite trial in adults used 125 mg twice a day, the same daily amount as two servings.
How is this different from the original capsules?
This formula adds 125 mg OEA and prints every ingredient amount on the label. It keeps 500 mg BIOMEnd® butyrate, 500 mg glucomannan, 150 mg African mango and 300 mcg chromium.
How and when should I take them?
Take 3 capsules with at least 12 oz of water, 30 minutes before a meal, once or twice a day. Leave at least 4 hours between servings. Before lunch is a great place to start.
How long does one bottle last?
Each bottle contains 84 capsules, or 28 servings of 3 capsules. One bottle lasts 28 days at one serving per day, or 14 days at two servings per day.
How quickly will I notice a difference?
Everyone’s different, which is why the 14-Day Ozzi Challenge exists. Take it for 14 straight days. If your cravings and food noise aren’t quieter, we’ll refund your first bottle.
Does it contain caffeine or stimulants?
No. There’s no caffeine, green tea extract or any other stimulant in the formula. Instead of blunting hunger with stimulants, it supports the fullness signals your gut already makes.†
Is this a GLP-1 medication?
No. It’s a dietary supplement, not a prescription GLP-1 medication, and it doesn’t work like one. Those medications supply a drug that acts like GLP-1. Ozzi supports the GLP-1 your own gut makes.† It isn’t a meal replacement or a treatment for any condition.
Why OEA and butyrate together?
They’re two different fullness pathways. OEA comes from the fat in your meal and signals through PPAR-alpha and GPR119. Butyrate comes from fiber and, in mouse and cell studies, stimulates the L-cells that release GLP-1 and PYY. Together they cover both ends of your gut’s fullness signaling.†
Can I take it if I use medication?
Consult your healthcare provider before use if you take any medication or have a medical condition. Do not use if you are under 18, pregnant, nursing or planning to become pregnant. Discontinue use and consult a healthcare professional if any adverse reaction occurs.
Does it contain allergens?
The label states that this product is manufactured in a facility that also processes products containing milk, eggs, fish, shellfish, tree nuts, peanuts, soy, wheat and sesame. See the full ingredient list and ask your healthcare provider if you have an allergy concern.
How is it different from the Ozzi drink?
These are different formulas and formats. Capsules contain OEA and are swallowed with water. The drink is mixed into water and has its own ingredient list and directions. Compare the labels before choosing the option that fits your routine.
Explore the drinkNATURAL METABOLISM SUPPORT†
Support your fullness signals.
Skip the stimulants.†
OEA, BIOMEnd® butyrate and konjac fiber.
Take it for 14 straight days. If your cravings and food noise aren’t quieter, we’ll refund your first bottle.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Individual results vary. Ingredient research did not test Ozzi’s finished formula.