BIOMEnd^®
ButyrateCapsules

Butyrate is a short-chain fatty acid made when gut bacteria ferment fiber. It is an important fuel source for the cells lining your colon. A butyrate supplement supplies a form of this compound directly.

Butyrate is a major fuel for colon cells and plays a role in maintaining the gut barrier. Mouse and cell research also explores its role in immune regulation, while human trials have investigated digestive symptoms with specific formulations.

Ozzi BIOMEnd provides daily gut and digestive support.† Explore the studies to see what researchers tested and found.

BIOMEnd combines a sodium-free ingredient structure with human absorption research. In a single-dose study in 10 healthy men, it produced about 5× the mean peak blood butyrate and 75% greater mean blood exposure over 3.5 hours than the tested tributyrin product. The mean observed peak was at 20 minutes versus 51.5 minutes. Differences from sodium butyrate were not statistically significant, and the study did not test Ozzi’s finished capsules. Each serving provides 1,000 mg of BIOMEnd® L-lysine butyrate.

The main difference is what carries the butyrate. Sodium butyrate pairs it with sodium. BIOMEnd pairs it with L-lysine, an essential amino acid. Tributyrin carries three butyrate groups on glycerol, which digestive enzymes can release.

Some tributyrin softgels also contain added oils. Ozzi’s formula has no added oils. Compare the full ingredient list and amount per serving: milligrams of one form are not automatically the same amount of butyric acid as milligrams of another.

They all provide a source of butyrate, the compound studied for colon-cell energy, gut-barrier function and immune signaling. That broader research helps explain why people take butyrate.

Forms can differ in how much butyrate they supply, where it is released and how it is absorbed. A result from one formulation is not automatically a result for every other one. We show the broader butyrate research alongside BIOMEnd’s own human absorption data.

No. The label lists 1,000 mg of L-Lysine Butyrate (as BIOMEnd®) per serving. This is the complete ingredient, including L-lysine. It is not a declaration of 1,000 mg of pure butyric acid.

Neither. Probiotics supply live microorganisms. Fiber is a material some gut microbes ferment to make compounds such as butyrate. BIOMEnd supplies L-lysine butyrate itself. It does not replace a varied, fiber-containing diet.

Human research has explored butyrate for digestive symptoms. In a randomized study of 66 people with IBS, microencapsulated sodium butyrate alongside existing treatment reduced how often certain symptoms occurred, without a significant improvement in symptom severity.

Those findings are specific to the tested formulation and population; they do not establish bloating or constipation relief from Ozzi BIOMEnd.

As a dietary supplement, take 4 capsules once daily with water. Each bottle contains 112 capsules, giving you 28 servings at the suggested daily amount.

The label directs you to take your daily serving with water. It does not specify taking them with or without food. Ask your healthcare professional if you need advice about timing for your circumstances.

Individual responses can differ. The published comparison reported no adverse events among 10 healthy men during its single-dose study. That small, short study does not establish how often side effects occur with daily use or with Ozzi’s finished capsules.

Ask your healthcare professional before use if you take medication, have a medical condition, are pregnant, or are breastfeeding. They can assess whether it fits your circumstances.

Check the complete formulas before combining supplements. Some Ozzi products already contain BIOMEnd, so taking both can increase your total intake. Ask your healthcare professional to review the products and serving amounts together.

No. This product supplies 1,000 mg of BIOMEnd per serving for daily gut support.† Crave Crusher Capsules are a separate product with a different formula. Follow the label for the product you have.

The supporting ingredients are Vegetable Capsule (Hypromellose), Silicon Dioxide, Dicalcium Phosphate and Microcrystalline Cellulose. Hypromellose forms the vegetable capsule shell.

The label states that this product is manufactured in a facility that also processes products which may contain milk, eggs, fish, shellfish, tree nuts, peanuts, soy, wheat and sesame. If you have a food allergy, review the full label with your healthcare professional before use.

L-lysine butyrate does not contain sodium in its chemical structure. Sodium butyrate does. Tributyrin also has no sodium in its structure, so this difference is specific to sodium-based forms.

BIOMEnd’s supplier describes its L-lysine butyrate ingredient as having a milder odor than traditional butyrate ingredients. A slight odor may still be present.

There is no established timeline for noticeable results with Ozzi BIOMEnd. The human ingredient study measured absorption after one dose, rather than how quickly people felt a digestive benefit. Take the product as directed; ongoing or worsening symptoms deserve medical advice.

GLP-1 is a hormone involved in appetite and blood-sugar regulation. Researchers have studied butyrate in laboratory models and in people, with findings that differ by formulation and study population. Those results do not establish that Ozzi’s BIOMEnd capsules raise GLP-1 or produce weight loss. This supplement is not a GLP-1 medication.

The ingredient absorption study on this page did not test those outcomes.